DRAFT: This module has unpublished changes.

 

Xingguo Cheng

Associate Professor

Department of Pharmaceutical Sciences

 

 

B.S.

Biology

Wuhan University, P. R. China

M.S.

Zoology

Wuhan University, P. R. China

Ph.D.

Toxicology

University of Kansas Medical Center, USA

Specialty: molecular toxicology and pharmacology, liver research, drug metabolism and transport, and Fgf21

 

Research Overview: Our current research focuses on characterization of toxicokinetics and toxicodynamics of endogenous chemicals and xenobiotics, especially the mechanistic roles of nuclear receptors (including AhR, CAR, PXR, PPARa, FXR, and Nrf2) and drug transporters (such as Mdrs, Mrps, and Oatps) in the disposition and action of drugs and nutrients.  Our laboratory is currently investigating: 1) the mode of action of toxicokinetics and toxicodynamics of perfluorochemicals, heavy metals and chemotherapeutic drugs, 2) the mechanistic roles of nuclear receptors and drug transporters in the modes of action of herbal medicine, 3) mechanistic investigation of psychoactive drugs, and 4) the pharmacological/toxicological investigation of fibroblast growth factor (Fgf) 21.

 

DRAFT: This module has unpublished changes.